1980-81 Regionalliga season

The 1980-81 Regionalliga season was the seventh season of the Regionalliga as the fourth-level of ice hockey in Germany. SV Bayreuth won the championship.

Regionalliga South

 * EV Mittenwald withdrew prior to the season.

Qualification round

 * TSV Farchant withdrew from the final round.

Regionalliga North

 * Altonaer SV withdrew.

Regionalliga North/West - Final round

 * The top two teams qualified for the Oberliga

Regionalliga Championship
Final:

SV Bayreuth - Königsborner SV 6:3  and 10:2